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WDR4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA530991
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: A549. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.Specifications
WDR4 | |
Polyclonal | |
Unconjugated | |
WDR4 | |
AI415180; AI448349; D530049K22Rik; hWH; mWH; Protein Wuho homolog; TRM82; TRM82 tRNA methyltransferase 82 homolog; TRMT82; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat domain 4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10785 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
0.71 mg/mL | |
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
P57081 | |
WDR4 | |
Recombinant protein fragment corresponding to a region within amino acids 98 and 365 of Human WDR4 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |