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Tocris Bioscience™ VZ 185
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Artikelnummer. 18797076
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Mængde:
5 mg
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18797076 5 mg
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Artikelnummer. 18797076 Leverandør Tocris Bioscience™ Leverandørnr. 6936/5

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Beskrivelse

Potent and selective BRD7/9 Degrader (PROTAC™)

Potent and selective VHL-based dual Degrader (PROTAC™) of BRD7/9 (DC50 values are 4 and 34 nM for BRD7 and BRD9, respectively). Exhibits selectivity for BRD7/9 degradation over other bromodomain-containing proteins and other BAF/PBAF subunits. Displays cytotoxicity towards EOL-1 and A-204 cancer cell lines.

Negative control cis VZ 185 (Cat. No. 6939) also available.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale (2S,4R)-N-(2-((5-(4-(2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)piperazin-1-yl)pentyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide
CAS 2306193-61-1
Mængde 5 mg
Molekylær formel C53H67FN8O8S
Renhed 98%
Produkttitel
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