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Invitrogen™ VPS34 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA146456

Produktkode 10018943

  • 3940.00 DKK / 100µL

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Beskrivelse

Beskrivelse

The target sequence has 87% sequence homology with xenopus. Suggested positive control: HepG2 whole cell lysates, antigen standard for PIK3C3 (transient overexpression lysate).

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

VPS34
Polyclonal
Unconjugated
Pik3c3
5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Rabbit
Antigen affinity chromatography
RUO
225326, 503700, 5289, 65052
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
0.2 mg/mL
PBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide
O88763, Q5D891, Q6PF93, Q8NEB9
Pik3c3
Synthetic peptide made to an internal portion of the human VPS34 protein (within residues 700-850).
100 μL
Primary
Human, Mouse, Rat, Pig
Antibody
IgG
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