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Voxtalisib, MedChemExpress

Artikelnummer. 16496908
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16496908 10 mg
16492967 50 mg
16483506 25 mg
16446986 100 mg
16429447 5 mg
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Artikelnummer. 16496908 Leverandør Medchem Express Leverandørnr. HY15900

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Beskrivelse

MedChemExpress Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.

Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.

Tekniske data

Kemisk navn eller materiale Voxtalisib
Fysisk form Solid
CAS 934493-76-2
Farve Brown
Mængde 10 mg
Renhedsgrad noter Research
Molekylær formel C13H14N6O
Til brug med (applikation) Cancer-Kinase/protease
Synonym XL765 SAR245409
Opløselighedsinformation DMSO : 10 mg/mL (37.00 mM; Need ultrasonic)
SMIL O=C1C(C2=NNC=C2)=CC3=C(C)N=C(N)N=C3N1CC
Molekylvægt (g/mol) 270.29
Formel vægt 270.29
Procent renhed 98.68%
Grad Research
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Research purposes only

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