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UNC2025 hydrochloride, MedChemExpress

Artikelnummer. 16495108
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16495108 10 mg
16461347 50 mg
16445836 100 mg
16427837 5 mg
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Artikelnummer. 16495108 Leverandør Medchem Express Leverandørnr. HY12344A

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Beskrivelse

MedChemExpress UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia.

UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM

Tekniske data

Kemisk navn eller materiale UNC2025 hydrochloride
CAS 2070015-17-5
Farve Light Yellow
Renhedsgrad noter Research
Molekylær formel C28H41ClN6O
Mængde 10 mg
Opløselighedsinformation H2O : 55 mg/mL (107.19 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (19.49 mM; Need ultrasonic)
SMIL CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C53)C=C2)CC1.[H]Cl
Molekylvægt (g/mol) 513.12
Formel vægt 513.12
Procent renhed 99.41%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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