missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Kemikalier
  4. Organiske forbindelser
  5. Organoheterocykliske forbindelser
  6. Pyridiner og derivater
  7. Tyk2-IN-5, MedChemExpress

Tyk2-IN-5, MedChemExpress

Artikelnummer. 16485376
Encompass_Preferred
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
5 mg
10 mg
25 mg
50 mg
100 mg
Pakningsstørrelse:
100mg
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde unitSize
16485376 100 mg 100mg
16484518 10 mg -
16453116 25 mg -
16450827 50 mg -
16417237 5 mg -
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 16485376 Leverandør Medchem Express Leverandørnr. HY111745

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

MedChemExpress Tyk2-IN-5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα. Highly effective in inhibiting IFNγ production in a rat pharmacodynamics model and fully efficacious in a rat adjuvant arthritis model.

Tyk2-IN-5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα. Highly effective in inhibiting IFNγ production in a rat pharmacodynamics model and fully efficacious in a rat adjuvant arthritis model.

Tekniske data

Kemisk navn eller materiale Tyk2-IN-5
CAS 1797432-62-2
Farve Light Green
Renhedsgrad noter Research
Molekylær formel C21H19FN8O2
Mængde 100 mg
Opløselighedsinformation DMSO : 43.33 mg/mL (99.74 mM; Need ultrasonic)
SMIL O=C1C(NC2=NN3C(C(NC)=C2)=NC=C3C(N[C@H]4[C@@H](F)C4)=O)=CC=CN1C5=CC=CC=N5
Molekylvægt (g/mol) 434.43
Formel vægt 434.43
Procent renhed 98.87%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
Vis mere Vis mindre

Research purposes only

Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.