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Tocris Bioscience™ Tubastatin A hydrochloride
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Artikelnummer. 18727978
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Mængde:
10 mg
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Artikelnummer. Mængde
18727978 10 mg
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Artikelnummer. 18727978 Leverandør Tocris Bioscience™ Leverandørnr. 6270/10

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Beskrivelse

Potent HDAC6 inhibitor

Tubastatin A hydrochloride is a potent HDAC6 inhibitor (IC50 = 0.015 μM). Exhibits some selectively for HDAC6 over HDAC8 and 1 (IC50 values are 0.854 and 16.4 μM, respectively). Induces elevated levels of α-tubulin and protects against glutathione-induced oxidative stress in primary neuronal cell culture. Reverses the axonal loss in peripheral neurons in a mouse model of Charcot-Marie-Tooth disease.
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Tekniske data

Kemisk navn eller materiale N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride
CAS 1310693-92-5
Analyseprocentområde >98%
Mængde 10 mg
Molekylær formel C20H21N3O2.HCl
Formel vægt Observed MW: 371.86
Produkttitel
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