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Tubastatin A Hydrochloride, MedChemExpress

Artikelnummer. 16476146
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Artikelnummer. 16476146 Leverandør Medchem Express Leverandørnr. HY13271

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Beskrivelse

MedChemExpress Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Tekniske data

Kemisk navn eller materiale Tubastatin A Hydrochloride
CAS 1310693-92-5
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C20H22ClN3O2
Mængde 100 mg
Synonym Tubastatin A HCl TSA HCl
Opløselighedsinformation DMSO : 10.8 mg/mL (29.04 mM; Need ultrasonic and warming) ∣H2O : 6.67 mg/mL (17.94 mM; Need ultrasonic)
SMIL O=C(C1=CC=C(C=C1)CN2C3=C(C4=C2C=CC=C4)CN(C)CC3)NO.[H]Cl
Molekylvægt (g/mol) 371.86
Formel vægt 371.86
Procent renhed 97.17%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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