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STEMCELL Technologies TTNPB
Beskrivelse
- TTNPB is an analog of retinoic acid that potently and selectively activates retinoic acid receptors (RAR; EC50 = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively; Beard et al.; Wong et al.)
- In combination with CHIR99021 or Activin A, induces intermediate mesoderm formation from human or mouse pluripotent stem cells, respectively (Araoka et al.; Oeda et al.)
- Promotes neuronal differentiation in cultured chick caudal neural plate explants (Diez del Corral et al.)
- Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells, in combination with CHIR99021, Tranylcypromine, VaLproic Acid, 3-Deazaneplanocin A, and E-616452 (Hou et al.)
- Induces the in vitro growth and differentiation to granulocytes of myeloid progenitors isolated from myelodysplastic syndrome (MDS) patients (Fabian et al.)
Tekniske data
Tekniske data
| CAS | 71441-28-6 |
| Synonym | AGN 191183; Arotinoid Acid; Ro 13-7410 |
| Mængde | 10 mg |
| Molekylær formel | C24H28O2 |
| Renhed | ≥98% |
Produkttitel
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