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Invitrogen™ TTC30A Polyclonal Antibody

Artikelnummer. 17100954 Shop alle Thermo Scientific produkter
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100 μg
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17100954 100 μg
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Artikelnummer. 17100954 Leverandør Invitrogen™ Leverandørnr. PA5113089
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    3475.00 DKK
    3092.75 DKK / 100µg
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    11% Slukket
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Forventet forsendelse: 03-12-2026
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Beskrivelse

Rabbit Polyclonal Antibody

TTC30A Polyclonal Antibody for Western Blot, IHC (P), ELISA

The TTC30A gene encodes for the Tetratricopeptide Repeat Domain 30A, which is part of the intraflagellar transport (IFT) complex B, critical for ciliary function. TTC30A and its paralog TTC30B are involved in the stability and functioning of the IFT complex. These proteins play a redundant role in maintaining cilia integrity, necessary for proper cellular signaling and homeostasis. Disruption of TTC30A, through CRISPR/Cas9 gene editing, has shown to impair ciliogenesis, leading to developmental defects such as limb malformations and polycystic kidney disease due to altered tubulin acetylation and ciliary transport. This highlights the importance of TTC30A in cellular and developmental processes.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen TTC30A
Applikationer ELISA, Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Koncentration 0.1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene TTC30A
Genadgangsnr. Q86WT1
Gene Alias IFT70A; tetratricopeptide repeat domain 30A; tetratricopeptide repeat domain 30B; tetratricopeptide repeat protein 30A; TPR repeat protein 30A; TTC30A
Gensymboler TTC30A
Værtsarter Rabbit
Immunogen Recombinant Human Tetratricopeptide repeat protein 30A protein (201-500AA).
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 92104
Målarter Human, Mouse
Indhold og opbevaring -20°C or -80°C if preferred
Produkttype Antibody
Form Liquid
Isotype IgG
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