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Trimetrexate, MedChemExpress

Artikelnummer. 16476627
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16476627 5 mg
16470267 50 mg
16453908 10 mg
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Artikelnummer. 16476627 Leverandør Medchem Express Leverandørnr. HY10373

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Beskrivelse

MedChemExpress Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.

Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.

Tekniske data

Kemisk navn eller materiale Trimetrexate
Fysisk form Solid
CAS 52128-35-5
Farve Yellow
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C19H23N5O3
Til brug med (applikation) COVID-19-immunoregulation
Synonym CI-898
Opløselighedsinformation DMSO : ≥ 61.5 mg/mL (166.48 mM)
SMIL NC1=C(C(C)=C2CNC3=CC(OC)=C(OC)C(OC)=C3)C(C=C2)=NC(N)=N1
Molekylvægt (g/mol) 369.42
Formel vægt 369.42
Procent renhed 99.22%
Grad Research
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Research purposes only

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