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Thermo Scientific™ Trimethoprim
Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial.
Brand: Thermo Scientific™ J63053.03
| Mængde | 1 g |
|---|
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Se returpolitik
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced
• Trimethoprim has antibacterial and antiprotozoal properties
Applications
• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects
• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression
Kemiske identifikatorer
| 738-70-5 | |
| 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine | |
| Powder | |
| White | |
| Trimethoprim is soluble in water at 0.4 mg/ml; It is also soluble in DMSO at 50 mg/ml and chloroform at 18.2 mg/ml |
| 290.32g/mol | |
| 2°C to 8°C | |
| An antibacterial and inhibitor of formylation. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme | |
| 199°C to 203°C |
Tekniske data
| 1 g | |
| 2°C to 8°C | |
| An antibacterial and inhibitor of formylation. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme | |
| C14H18N4O3 | |
| 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine | |
| Trimethoprim is soluble in water at 0.4 mg/ml; It is also soluble in DMSO at 50 mg/ml and chloroform at 18.2 mg/ml |
| White | |
| Powder | |
| 738-70-5 | |
| 290.32g/mol | |
| 199°C to 203°C | |
| 625127 |
Sikkerhed og håndtering
Produktidentifikator
Signalord
Farekategori
Faresætning
Sikkerhedssætning
Supplerende oplysninger
- Trimethoprim
Signalord
- Advarsel
Farekategori
- Akut toksicitet Kategori 4
Faresætning
- H302-Farlig ved indtagelse.
Sikkerhedssætning
- P264-Vask grundigt efter brug.
- P301+P330+P331-I TILFÆLDE AF INDTAGELSE: Skyl munden. Fremkald IKKE opkastning.
- P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .
Supplerende oplysninger
- MIXTURE LIST-Indeholder: Trimethoprim
Produkttitel
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