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Tocris Bioscience™ tri-GalNAc-PEG3-Azide
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Artikelnummer. 18786275
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Mængde:
1 mg
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18786275 1 mg
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Artikelnummer. 18786275 Leverandør Tocris Bioscience™ Leverandørnr. 8015/1

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Beskrivelse

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

tri-GalNAc-PEG3-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; each molecule incorporates three ASGPR ligands with a PEG3 linker and azide group reactive handle ready for conjugation. Upon binding to the ASGPR, tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.
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Tekniske data

CAS 2925590-71-0
Mængde 1 mg
Mål Degrader Building Blocks
Molekylær formel C70H125N13O31
Renhed 0.9
Produkttitel
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