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  6. Transglutaminase 2/TGM2 Antibody (TGM2/419), R&D Systems™

Transglutaminase 2/TGM2 Antibody (TGM2/419), R&D Systems™

Artikelnummer. 18600856 Shop alle Bio Techne produkter
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Artikelnummer. 18600856 Leverandør Novus Biologicals Leverandørnr. NBP2445940.1mg
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    4194.23 DKK
    3571.05 DKK / 0.1mg
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Forventet forsendelse: 26-11-2026
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Beskrivelse

A Novus product, part of R&D Systems. Mouse Monoclonal Antibody

Transglutaminase 2/TGM2 Monoclonal specifically detects Transglutaminase 2/TGM2 in Human, Monkey, Mouse, Rabbit, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Transglutaminase 2/TGM2
Applikationer Immunohistochemistry, Western Blot
Klassifikation Monoclonal
Klon TGM2/419
Koncentration 0.2mg/mL
Konjugeret Unconjugated
Fortynding Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulering 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Genadgangsnr. P21980
Gene Alias C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2
Gensymboler TGM2
Værtsarter Mouse
Immunogen Recombinant full-length human TGM2 protein
Oprensningsmetode Protein A or G purified
Mængde 0.1 mg
Regulatorisk status RUO
Forskningsdisciplin Apoptosis, Immune System Diseases, Immunology, Signal Transduction
Primær eller sekundær Primary
Gen-id (Entrez) 7052
Testspecificitet Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Målarter Human, Monkey, Mouse, Rabbit, Rat
Indhold og opbevaring Store at 4C.
Produkttype Antibody
Form Purified
Isotype IgG2a κ
Produktlinje Novus
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For Research Use Only

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