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Tocris Bioscience™ Trametinib
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Artikelnummer. 18746376
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18746376 10 mg
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price
Artikelnummer. 18746376 Leverandør Tocris Bioscience™ Leverandørnr. 7709/10
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    1157.10 DKK / 10mg
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Forventet forsendelse: 18-09-2026
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Denne vare kan ikke returneres. Se returpolicy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price

Beskrivelse

Potent and selective MEK inhibitor; orally bioavailable

Trametinib is a potent and selective MEK1 and MEK2 inhibitor (IC50 = 0.92 and 1.8 nM, respectively, in cell-free assays). In vitro, it inhibits the growth of human colorectal cancer cell lines expressing either B-RAF or K-RAF (IC50 values range from 0.48 to 36 nM). In vivo, it suppresses tumor growth of HT-29 and COLO205 xenografts in nude mice. Trametinib induces apoptosis. This compound is orally bioavailable.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2 H)-yl]phenyl]acetamide
CAS 871700-17-3
Mængde 10 mg
Mål MEK Inhibitors
Molekylær formel C26H23FIN5O4
Renhed 0.98
Produkttitel
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