missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. 18755546

Tocris Bioscience™ TL 13-112
GREENER_CHOICE

Artikelnummer. 18755546
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
5 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde
18755546 5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 18755546 Leverandør Tocris Bioscience™ Leverandørnr. 6745/5

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Selective ALK Degrader (PROTAC™)

Selective anaplastic lymphoma kinase (ALK) degrader (DC50 values are 10 and 40 nM in H3122 and Karpas 299 cells, respectively). Comprises the cereblon E3 ligase ligand Pomalidomide (Cat. No. 6302) conjugated to an ALK inhibitor. Inhibits proliferation of ALK-positive cancer cell lines. Maximum degradation exhibited at 16 h.

Negative control TL 13-110 (Cat. No. 6746) also available.

TL 13-112 is a selective anaplastic lymphoma kinase (ALK) Degrader (PROTAC®) (DC50 values are 10 and 40 nM in H3122 and Karpas 299 cells, respectively). Comprises the cereblon E3 ligase ligand Pomalidomide (Cat. No. 6302) conjugated to an ALK inhibitor. Inhibits proliferation of ALK-positive cancer cell lines. Maximum degradation exhibited at 16 h.

Negative control TL 13-110 (Cat. No. 6746) also available.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale N-[2-[2-[2-[4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetamide
CAS 2229037-19-6
Mængde 5 mg
Molekylær formel C49H60ClN9O10S
Formel vægt 1002.57
Renhed 98%
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.