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TOKU-E™ Timentin ReadyMade™ Solution
Beskrivelse
- CAS Number: 116876-37-0
- Molecular Formula: C15H14N2Na2O6S2 / C8H8KNO5
- Molecular Weight: 665.64 g/mol (combined)
- Storage Conditions: -20°C
- Form: Liquid
- Source: Semi-synthetic
- Spectrum: Timentin is broad-spectrum and has activity against Gram-negative cocci other than enterococci and methicillin-resistant staphylococci; Enterobacteriaceae, including drug-resistant strains; and anaerobes
- Mechanism of Action: Timentin interferes with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Clavulanic acid is a 'suicide' or 'mechanism based' β-lactamase inhibitor. Clavulanic acid contains a β-lactam ring that binds strongly to β-lactamase at or near its activation site, thereby permanently inhibiting enzymatic activity. This action protects other beta-lactam antibiotics (penicillins, cephalosporins, etc.) from β-lactamase catalysis, thereby enhancing their antibacterial activity
Tekniske data
Tekniske data
| Kemisk navn eller materiale | Ticarcillin Disodium with Clavulanate Potassium 15:1 |
| Fysisk form | Liquid |
| CAS | 116876-37-0 |
| Kilde | Semi-synthetic |
| Emballage | 2 mL plastic vial |
| Steril filtreret | Yes, 0.22 μm |
| Sterilitet | Sterile |
| Farve | Colorless |
| Koncentration | 95 to 105 mg/mL |
| Mængde | 10 x 1 ml |
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Produkttitel
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