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STEMCELL Technologies Thiazovivin
Beskrivelse
- Thiazovivin is a selective inhibitor of Rho-associated coiled-coil containing protein kinase (ROCK), a serine/threonine kinase that plays a role in cell polarity, contraction, and actin cytoskeleton reorganization (Xu et al.) Thiazovivin is effective at 5-fold-lower concentrations than another common ROCK inhibitor Y-27632 (Catalog #72302; Xu et al.)
- Promotes survival of human embryonic stem (ES) cells during dissociation by stabilizing E-cadherin and improves cell attachment (Xu et al.)
- Promotes survival of single human induced pluripotent stem (iPS) cells during transfection for TALEN-mediated genome editing (Sun and Zhao)
- Increases the efficiency of reprogramming human somatic cells to iPS cells, in combination with PD0325091 and SB431542 (Lin et al.)
- Increases the efficiency of reprogramming human cord blood mononuclear cells to iPS cells (Hu et al.)
Tekniske data
Tekniske data
| CAS | 1226056-71-8 |
| Synonym | Tzv |
| Mængde | 5 mg |
| Molekylær formel | C15H13N5OS |
| Renhed | ≥98% |
Produkttitel
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