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Thermo Scientific™ TheraPure 2ʹ-OMe-U Phosphoramidite

Artikelnummer. 17977152 Shop alle Thermo Scientific produkter
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Mængde:
1 g
Format:
Amber Bottle (20-400 Thread)
Serum Vial Bottle
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Artikelnummer. Mængde Format
17977152 1 g Amber Bottle (20-400 Thread)
17907162 1 g Serum Vial Bottle
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Artikelnummer. 17977152 Leverandør Thermo Scientific™ Leverandørnr. 27204410
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Forventet forsendelse: 08-10-2026
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Beskrivelse

2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in an amber bottle.

2'-OMe-U CEP er en phosphoramidit indeholdende 5' DMT og nukleosidet uridin (U) med 2'-O-methyl beskyttelse, til brug i oligonukleotidsyntese. Placeret i den ideelle oligoposition viser 2'-O-methyl (OMe) oligo-modifikationer nuklease-resistens, færre off-target-effekter og let øgede hybridiseringsaffiniteter. Disse phosphoramiditter bruges almindeligvis til oligoer designet til antisense, siRNA, aptamer eller gRNA-baseret forskning. De TheraPure varemærke angiver vores højeste niveau af phosphoramidit-renhed, udviklet med den største stringens af high definition analytics og stramt kontrollerede urenhedsprofiler og derfor ideel til enhver terapeutisk anvendelse. Dette produkt leveres i en 30 ml ravfarvet flaske med en 20-400 finish hals stil, som er kompatibel med de fleste Expedite synthesizere.

Funktioner:
•Fuldt kemisk navn: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridin-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidit
•Molekylformel: C 40 H 56 N 7 O 9 P
•Base: U
•Formelvægt: 760,8 g/mol
• CAS nummer: 110764-79-9
•HPLC renhed:≥ 99%; M-11 Urenhed:≤ 0,01%; Enkelt kritisk urenhed≤ 0,3 %
•31P NMR renhed: >99%; Summen af ikke-primære toppe ved 140-152 ppm≤ 0,5 %

TRUSTED_SUSTAINABILITY

Tekniske data

Format Amber Bottle (20-400 Thread)
Til brug med (udstyr) Expedite synthesizere
Produkttype 2i-OMe-U CEP
Indhold og opbevaring Opbevares i fryseren (ved eller under -20 °C).
Nukleosid type Uridin (U)
Reagensfunktioner 2-i-OMe modificeret
Forsendelsestilstand Stuetemperatur
Renhed 99%
Mængde 1 g
Reagenstype Phosphoramidite
Grad TheraPure™
Nukleinsyretype RNA
Produktlinje TheraPure
Form Pulver
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