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  7. tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

Catalog Number 11494364
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Quantity:
5 g
25 g
100 g
18162-48-6
C6H15ClSi
150.721
MFCD00000501
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
28928
CHEBI:85071
tert-butyl-chloro-dimethylsilane
CC(C)(C)[Si](C)(C)Cl
18162-48-6
C6H15ClSi
150.721
MFCD00000501
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
28928
CHEBI:85071
tert-butyl-chloro-dimethylsilane
CC(C)(C)[Si](C)(C)Cl

Description

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
TRUSTED_SUSTAINABILITY
Boiling Point 124°C to 126°C
Melting Point 86°C to 89°C
Quantity 100 g
Linear Formula (CH3)3CSi(CH3)2Cl
UN Number UN2925
Beilstein 505999
Flash Point 22°C (72°F)
Solubility Information Soluble in chloroform and ethyl acetate. Insoluble in water.
Formula Weight 150.73
Percent Purity 97%
Odor Pungent
Sensitivity Moisture sensitive
Density 0.81
Chemical Name or Material tert-Butyldimethylchlorosilane
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