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TCOF1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11003-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Treacle is a serine/alanine-rich 1,411 amino acid nuclear phosphoprotein that interacts with upstream binding factor (UBF) and affects transcription of the ribosomal DNA gene. Treacle is also involved in early embryonic development, particularly in the craniofacial complex, and may play a role in nucleolarcytoplasmic transport. The Treacle protein contains three domains with unique N- and C-termini and a large central repeat domain. Mutations in TCOF1, the gene that encodes for Treacle, cause Treacher Collins-Franceschetti syndrome (TCS), a disorder characterized by defects in craniofacial development. Symptoms of TCS include conductive hearing loss, hypoplasia of the mandible and maxilla, downward sloping palpebral fissures and cleft palate.Specifications
TCOF1 | |
Polyclonal | |
Unconjugated | |
TCOF1 | |
MFD1, TCOF1, treacle, Treacle protein | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
21453, 6949 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
O08784, Q13428 | |
TCOF1 | |
TCOF1 Fusion Protein Ag1447 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |