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Thermo Scientific™ Tango™ GPR39-bla U2OS Cells

Brand: Thermo Scientific™ K1842

Product Code. 10491405

95300.00 DKK / Each

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Description

Tango™ GPR39-bla U2OS cells contain the orphan human G-protein Coupled Receptor 39 (GPR39) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR39-bla U2OS cells have been functionally validated for a receptor specific response to FBS. In addition, Tango™ GPR39-bla U2OS cells have been tested for assay performance under variable conditions.

Specifications

Accession Number	NM_001508.1
Cell State	Dividing Cells
Cytoplasmic Tail	Native Tail
For Use With (Application)	FRET
Human Protein Class	G-Protein Coupled Receptor (GPCR)
Population Status	Pool of Stable Cells
Quantity	8 x 10⁶ Cells
Target Entry	GPR39
Cell Line	U2OS
Druggable Target	GPCR

Assay Entry	Cell-based beta-arrestin recruitment
Content And Storage	LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • Tango™ GPR39-UAS-bla CHO-K1 cells • Tango™ GPR39-UAS-bla CHO-K1 Assay Protocol • Certificate of Analysis The Tango™ GPR39-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method	Fluorescence
Gene Symbol	GPR39
Includes	GPR39-UAS-bla CHO-K1 cells, GPR39-UAS-bla CHO-K1 Assay Protocol, Certificate of Analysis
Product Line	Tango™
Readout	End Point
Type	Dividing Cells
System Type	Tango™

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Thermo Scientific™ Tango™ GPR39-bla U2OS Cells

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