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Tocris Bioscience™ SZL P1-41
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Artikelnummer. 18795668
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10 mg
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18795668 10 mg
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Artikelnummer. 18795668 Leverandør Tocris Bioscience™ Leverandørnr. 5076/10

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Beskrivelse

Selective Skp2 inhibitor

SZL P1-41 is a Skp2 inhibitor; thought to prevent assembly of Skp2-Skp1 complexes. Selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. Also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. Suppresses the survival of cancer cells and cancer stem cells by triggering cell senescence and inhibiting glycolysis. Exhibits antitumor effects in multiple animal models and cancer cell lines.
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Tekniske data

Kemisk navn eller materiale 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one
CAS 222716-34-9
Mængde 10 mg
Molekylær formel C24H24N2O3S
Formel vægt 420.52
Renhed 98%
Produkttitel
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