Invitrogen™ Streptococcus agalactiae Monoclonal Antibody (Strep12-424.1), Invitrogen™

Beskrivelse

MA1-10871 specifically detects Streptococcus agalactiae. This antibody does not cross react with the Streptococcus species: dysgalactiae, uberis, bovis, and faecalis; the Mycoplasma species: bovis, californicum, and genitalium; as well as Staphlyococcus aureus, E. coli, and Corynebacterium bovis. MA1-10871 has been successfully used in ELISA applications. The MA1-10871 immunogen is UV-inactivated Strep agalactiae cells isolated from mastitic milk.

Once thought to infect only cows, where it produces mastitis, Streptococcus agalactiae is now known to be able to cause serious disease, bacteremia and meningitis, in immunocompromised individuals and in neonates. Infections in the newborn are the most common and are extremely serious. They are of two types. Early onset of infection, usually occuring within 5 days of birth, is manifested by bacteremia and pneumonia. This infection is contracted vertically, as the baby passes through the birth canal. The other type of infection is a meningitis that occurs between the 10th and 60th days of life. The origin of this infection is not known, but it is not believed to be the mother.