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Invitrogen™ STOML1 Polyclonal Antibody
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Artikelnummer. 13289088
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Mængde:
100 μL
Pakningsstørrelse:
100µg
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13289088 100 μL 100µg
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Artikelnummer. 13289088 Leverandør Invitrogen™ Leverandørnr. PA521557

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Beskrivelse

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4. Predicted reactivity: Mouse (84%), Rat (83%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen STOML1
Applikationer Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene STOML1
Genadgangsnr. Q9UBI4
Gene Alias 1810015E19Rik; AI847431; EPB72-like 1; EPB72-like protein 1; hUNC-24; MSTP019; Protein unc-24 homolog; RGD1559463; SLP1; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin like 1; stomatin-like 1; stomatin-like protein 1; Stomatin-related protein; STOML1; STORP; UNC24; WPB72
Gensymboler STOML1
Værtsarter Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human STOML1. The exact sequence is proprietary.
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 9399
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG
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