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Tocris Bioscience™ SSR 149415
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Artikelnummer. 18745636
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10 mg
50 mg
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Artikelnummer. Mængde
18745636 10 mg
18756176 50 mg
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Artikelnummer. 18745636 Leverandør Tocris Bioscience™ Leverandørnr. 6195/10

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Beskrivelse

Potent and selective vasopressin V1B antagonist

SSR 149415 is a potent and selective vasopressin V1B antagonist (Ki values are 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Displays >70-fold selectively for rat V1B over V1A, V2 oxytoxin and a range of other receptors and ion channels. Inhibits AVP-induced glucagon release in In-R1-G9 α-pancreatic cells in vitro. Inhibits stress-induced ACTH release and exhibits anxiolytic-like effects in anxiety models. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide
CAS 439687-69-1
Analyseprocentområde >98%
Mængde 10 mg
Molekylær formel C30H32ClN3O8S
Formel vægt Observed MW: 630.11
Produkttitel
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