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Invitrogen™ SS18 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA563745

Produktkode 15791512

  • 4365.00 DKK / 100µL

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Immunogen sequence: NGQMPGPNHM PMQGPGPNQL NMTNSSMNMP SSSHGSMGGY NHSVPSSQSM P Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

SS18
Polyclonal
Unconjugated
SS18
D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; synovial sarcoma-associated Ss18-alpha; SYT
Rabbit
Antigen affinity chromatography
RUO
6760
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q15532
SS18
Recombinant protein corresponding to Human SS18. Recombinant protein control fragment (Product #RP-101810).
100 μL
Primary
Human
Antibody
IgG
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