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SPP-86, MedChemExpress

Artikelnummer. 16497077
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Mængde:
5 mg
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Artikelnummer. Mængde
16497077 5 mg
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Artikelnummer. 16497077 Leverandør Medchem Express Leverandørnr. HY110193

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Beskrivelse

MedChemExpress SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.

SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.

Tekniske data

Kemisk navn eller materiale SPP-86
Fysisk form Solid
CAS 1357349-91-7
Farve Light Nude
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C16H15N5
Til brug med (applikation) Neuroscience-Neuromodulation
Opløselighedsinformation DMSO : 100 mg/mL (360.59 mM; Need ultrasonic)
SMIL CC(C)N1C2=NC=NC(N)=C2C(C#CC3=CC=CC=C3)=N1
Molekylvægt (g/mol) 277.32
Formel vægt 277.32
Procent renhed 98.04%
Grad Research
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Research purposes only

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