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Sodium deoxycholate, 97%, Thermo Scientific™

Sodium deoxycholate, CAS # 302-95-4, is a bile acid salt that contains a deoxycholate group and shows choleretic activity. It is used as a biological detergent to lyse cells and to solubilize cellular and membrane components.

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Kemiske identifikatorer

CAS 302-95-4
Molekylær formel C24H39NaO4
Molekylvægt (g/mol) 414.562
MDL nummer MFCD00064139
InChI nøgle FHHPUSMSKHSNKW-WGRCLTAPSA-M
Synonym sodium deoxycholate
PubChem CID 91810855
IUPAC navn sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
SMIL CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
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Produktkode Brand Mængde Pris Antal & tilgængelighed  
15414699
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Thermo Scientific Alfa Aesar
J62288.30 		250g
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Beskrivelse

Beskrivelse

Sodium deoxycholate is used as a choleretic and an anionic detergent. It is useful for the extraction of membrane receptors, plasma membrane proteins, nuclei isolation and solubilizes fats as well as membrane components. It acts as an intermediate for the production of corticosteroids and microbiological diagnostic media. In addition, it acts as a catalyst in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins.

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Sodium deoxycholate is a bile salt and an ionic detergent
• It is a bile acid formed by bacterial action from cholate
• Sodium deoxycholate is considered to be a cholagogue and choleretic since it promotes the flow of bile into the duodenum (cholagogues) or stimulates bile production by the liver (choleretic)

Application

• In chemical approaches, sodium deoxycholate acts as an intermediate for corticosteroid production
• This compound is used to lyse cells and to extract cellular and membrane components, including membrane receptors, plasma membrane proteins, and nuclei, and allows the solubilization of fats for intestinal absorption and membrane components
• Sodium deoxycholate is also used to prepare microbiological diagnostic media and acts as a catalyst in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
• In biological experiments, sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue
• It is also used in the decellularization of aortic valvular conduit

Tekniske data

Kemiske identifikatorer

302-95-4
414.562
FHHPUSMSKHSNKW-WGRCLTAPSA-M
91810855
CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
C24H39NaO4
MFCD00064139
sodium deoxycholate
sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Tekniske data

Sodium deoxycholate
C24H39NaO4
3581950
Soluble in waterSoluble in water,dimethyl sulfoxide and methanol; Slightly soluble in ethanol.
CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
414.562
414.6
302-95-4
MFCD00064139
sodium deoxycholate
FHHPUSMSKHSNKW-WGRCLTAPSA-M
sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
91810855
97%
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Sikkerhed og håndtering

Sikkerhed og håndtering

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P301+P312-P304+P340-P312-P330-P501c

H302-H335

missing translation for 'einecsNumber' : 206-132-7

missing translation for 'rtecsNumber' : FZ2250000

missing translation for 'tsca' : Yes

Anbefalet opbevaring : Ambient temperatures

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RUO – Research Use Only

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