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SKF-96365 hydrochloride, MedChemExpress

Artikelnummer. 16485467
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Pakningsstørrelse:
10mg
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16485467 5 mg -
16462728 10 mg 10mg
16460896 200 mg -
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Artikelnummer. 16485467 Leverandør Medchem Express Leverandørnr. HY1000015mg

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Beskrivelse

MedChemExpress SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.

SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.

Tekniske data

Kemisk navn eller materiale SKF-96365 hydrochloride
CAS 130495-35-1
Farve White
Renhedsgrad noter Research
Molekylær formel C22H27ClN2O3
Mængde 5 mg
Opløselighedsinformation DMSO : 100 mg/mL (248.19 mM; Need ultrasonic) ∣H2O : 100 mg/mL (248.19 mM; Need ultrasonic)
SMIL COC1=CC=C(CCCOC(C2=CC=C(OC)C=C2)CN3C=CN=C3)C=C1.[H]Cl
Molekylvægt (g/mol) 402.91
Formel vægt 402.91
Procent renhed 99.51%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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