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SIRT5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Artikelnummer. 16894154 Shop alle Proteintech produkter
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20 μL
150 μL
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16894154 20 μL
16884154 150 μL
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Artikelnummer. 16894154 Leverandør Proteintech Leverandørnr. 151221AP20UL

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Beskrivelse

Rabbit Polyclonal Antibody

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

Tekniske data

Antigen SIRT5
Applikationer Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Western Blot
Klassifikation Polyclonal
Koncentration 0.27 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SIRT5
Genadgangsnr. Q68FX9, Q8K2C6, Q9NXA8
Gene Alias SIR2 like protein 5, SIR2L5, SIRT5
Gensymboler Sirt5
Værtsarter Rabbit
Immunogen SIRT5 Fusion Protein Ag7195
Oprensningsmetode Antigen Affinity Chromatography
Mængde 20 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 23408, 306840, 68346
Målarter Rat, Human, Mouse
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG
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