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Tocris Bioscience™ Selpercatinib Product Code.: 18747026

Tocris Bioscience™ Selpercatinib
GREENER_CHOICE

Product Code. 18747026
10 mg, 10mg
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18747026

Brand: Tocris Bioscience™ 7696/10

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This item is not returnable. View return policy

Potent and selective RET inhibitor

Selpercatinib, is a potent and selective receptor tyrosine kinase RET inhibitor (EC50 = 4 nM). It shows > 100-fold selectivity for > 95% of 228 purified kinase domains in radiometric assays. In vitro, it inhibits proliferation of cancer cell lines containing RET mutations or gene fusions. In vivo, it inhibits tumor growth in diverse RET mouse models. Selpercatinib is orally bioavailable.
Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 6-(2-Hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1 ]hept-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
CAS 2152628-33-4
Quantity 10 mg
Target Ret
Molecular Formula C29H31N7O3
Purity 0.98
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