missing translation for 'onlineSavingsMsg'
Få mere at vide
Få mere at vide
Beskrivelse
Selinexor is an inhibitor of the exportin 1 (XPO1/CRM1) nuclear exporter. Shows selectivity for TNBC over ER-positive breast cancer cell lines (IC50 values are 11-550 nM and >1000 nM, respectively), and reduces growth of xenografts. Inhibits growth of thyroid cancer cell lines (IC50 = 150-500 nM), potentiates the anti-tumor effects of Olaparib (Cat. No. 7579) in ovarian cancer and breast cancer. Also a potent inhibitor of SARS-CoV-2 replication in vitro (EC50 = 10 nM) and downregulates the production of pro-inflammatory cytokines including TNF-α and IL-6.
Greener Choice-anprisninger
- undefined
- Ozone-Safe or Safe for the Ozone Layer

Tekniske data
Tekniske data
Kemisk navn eller materiale | (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide |
CAS | 1393477-72-9 |
Mængde | 10 mg |
Mål | Antiviral Compounds |
Molekylær formel | C17H11F6N7O |
Kampagner
-
Multiple Manufacturers
Genomics Powerhouse
Power your pipeline from PCR to sequencing.Promo Code: 24117Expires: 2025-08-24
Days
10Hours
19Minutes
0Seconds
14
Korrektion af produktindhold
Dit input er vigtigt for os. Udfyld denne formular for at give feedback relateret til indholdet på dette produkt.
Produkttitel
Tocris Bioscience™ Selinexor >
Ser du en mulighed for forbedring?Del en indholdskorrektion