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Selexipag

Product Code. 30001476
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50 mg
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30001476 10 mg
30001480 50 mg
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Product Code. 30001476 Supplier Tocris Bioscience Supplier No. 3351/10

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Description

Selective prostacyclin IP1 receptor agonist

6243Selective prostacyclin IP1 receptor agonist (Ki values are 260 and 2100 nM and for human and rat IP receptors, and >10 μM for EP1-4, DP, FP, and TP receptors). Prodrug for the active form of MRE 269. Ameliorates vascular endothelial dysfunction and increases femoral skin blood flow in rats. Orally available.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 475086-01-2
Molekylær formel C26H32N4O4S
Molekylvægt (g/mol) 496.63
MDL nummer MFCD10567093
InChI nøgle QXWZQTURMXZVHJ-UHFFFAOYSA-N
Synonym selexipag, uptravi, unii-5exc0e384l, 2-4-5,6-diphenylpyrazin-2-yl isopropyl amino butoxy-n-methylsulfonyl acetamide, 2-4-5,6-diphenylpyrazin-2-yl propan-2-yl amino butoxy-n-methanesulfonyl acetamide, 2-4-n-5,6-diphenylpyrazin-2-yl-n-isopropylamino butyloxy-n-methylsulfonyl acetamide, selexipag usan:inn, uptravi tn, ns-304 selexipag
PubChem CID 9913767
IUPAC navn 2-{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}-N-methanesulfonylacetamide
SMIL CC(C)N(CCCCOCC(=O)NS(C)(=O)=O)C1=CN=C(C2=CC=CC=C2)C(=N1)C1=CC=CC=C1

Specifications

Kemisk navn eller materiale NS 304
Mængde 10 mg
Formel vægt 496.62
Procent renhed >98%
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