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Invitrogen™ SBF1 Polyclonal Antibody

Beskrivelse
Immunogen sequence: CYDSCPRAQP DAISRLLEEL QRLETELGQP AERWKDTWDR VKAAQRLEGR PDGRGTPSSL LVSTAPHHRR SLGVYL Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.
Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Tekniske data
Tekniske data
| Antigen | SBF1 |
| Applikationer | Immunocytochemistry |
| Klassifikation | Polyclonal |
| Koncentration | 0.5 mg/mL |
| Konjugeret | Unconjugated |
| Formulering | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Sbf1 |
| Genadgangsnr. | O95248 |
| Gene Alias | CMT4B3; DENN/MADD domain containing 7A; DENND7A; Inactive phosphatidylinositol 3-phosphatase 5; MTMR5; Myotubularin-related protein 5; Sbf1; SET binding factor 1; SET-binding factor 1 |
| Gensymboler | Sbf1 |
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Produkttitel
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