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Tocris Bioscience™ SB 290157 trifluoroacetate
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Artikelnummer. 18735426
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Mængde:
5 mg
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Artikelnummer. Mængde
18735426 5 mg
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Artikelnummer. 18735426 Leverandør Tocris Bioscience™ Leverandørnr. 6860/5

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Beskrivelse

Potent C3a receptor antagonist

SB 290157 trifluoroacetate is a potent C3a receptor antagonist (IC50 values are 27 - 30 nM for C3a-induced Ca2+ mobilization in vitro and ex vivo). Inhibits C3a-induced chemotaxis in human mast cell line. Also inhibits tau hyperphosphorylation in vitro. Displays anti-inflammatory effects in animal models of airway inflammation and arthritis. Also inhibits glucose-induced insulin secretion and ATP production from ex vivo human and mouse pancreatic islets. Also exhibits C3a receptor agonist activity.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate
CAS 1140525-25-2
Mængde 5 mg
Molekylær formel C22H28N4O4.CF3CO2H
Renhed 97%
Produkttitel
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