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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera Recombinant Protein

Artikelnummer. 17986241
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100 μg
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Artikelnummer. Mængde
17986241 100 μg
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Artikelnummer. 17986241 Leverandør Invitrogen™ Leverandørnr. RP88398
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    4050.00 DKK
    3402.00 DKK / 100µg
    Spare 648.00 DKK
    16% Slukket
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Forventet forsendelse: 15-12-2026
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Beskrivelse

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Tekniske data

Til brug med (applikation) Binding Assay, Control, ELISA Standard
Format Lyophilized
Formulering PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Molekylvægt (g/mol) 51.54 kDa
Navn SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera
pH-område 7.4
Oprensningsmetode Purified
Mængde 100 μg
Opbevaringskrav -20°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Endotoksin koncentration <1.0 EU/μg
Gene Alias Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Fælles navn SARS-CoV-2 Spike Protein RBD
Biologisk aktivitet The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Produkttype Protein
Konjugeret Unconjugated
Rekombinant Recombinant
Protein tag Fc-tag
Sekvens SARS-CoV-2 spike RBD (Accession # YP_009724390.1), amino acids Arg319-Phe541 with a V367F substitution and a C-terminal mouse IgG1 Fc region
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Aktivitet The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Udtrykssystem HEK293 cells
Form Lyophilized
Renhed eller kvalitetsklasse >90% as determined by SDS-PAGE.
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