missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Antistoffer
  4. Primære antistoffer
  5. Alle primære antistoffer
  6. 11505802

Invitrogen™ Ryanodine Receptor Monoclonal Antibody (C3-33)
GREENER_CHOICE

Artikelnummer. 11505802
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
100 μg
Pakningsstørrelse:
100µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde unitSize
11505802 100 μg 100µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 11505802 Leverandør Invitrogen™ Leverandørnr. MA3916

Please to purchase this item. Need a web account? Register with us today!

Edge
Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Mouse Monoclonal Antibody

MA3-916 detects ryanodine receptor 2 (RyR2) and shows cross-reactivity with RyR1 in amphibian, canine, chicken, fish, guinea pig and rat tissues. MA3-916 has been successfully used in Western blot, immunohistochemical, immunofluorescence, immunocytochemistry and immunoprecipitation procedures. By Western blot, this antibody detects a 565 kDa protein representing the ryanodine receptor. In non-mammalian vertebrates, a doublet is seen at 565 kDa representing the alpha and beta isoforms of the receptor. Immunohistochemical staining of RyR in rat cardiac tissue with MA3-916 results in intense staining of the myofiber, which is consistent with sarcoplasmic reticulum localization.

The ryanodine receptor (RyR) is the channel responsible for the release of calcium from the sarcoplasmic reticulum (SR) in muscle cells and also plays a role in calcium regulation in non-muscle cells. The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains; the remainder of the protein, termed the 'foot' region is located in the cytoplasm between the T-tubule and the SR. The mammalian RyR is the product of three different genes: RyR-1, which is expressed predominantly in skeletal muscle and areas of the brain, RyR-2, which is expressed predominantly in the heart muscle but also found in the stomach, endothelial cells and diffuse areas of the brain, and RyR-3 which is found in smooth muscle and the brain (striatum, thalamus and hippocampus).
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Ryanodine Receptor
Applikationer Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon C3-33
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.05% sodium azide
Gene RYR1
Genadgangsnr. B0LPN4, E9PZQ0, E9Q401, F1LMY4, P11716, P21817, P30957, Q92736
Gene Alias 9330127I20Rik; AI528790; ARVC2; ARVD2; Ca2+ release channel; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac muscle-type ryanodine receptor; cardiac ryanodine receptor; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; CCO; central core disease of muscle; islet-type ryanodine receptor; kidney-type ryanodine receptor; LOW QUALITY PROTEIN: ryanodine receptor 1; MHS; MHS1; PPP1R137; protein phosphatase 1, regulatory subunit 137; ryanodine receptor; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RYDR; Ryr; RYR1; RYR-1; Ryr1l; Ryr2; RYR-2; sarcoplasmic reticulum calcium release channel; skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; SKRR; Type 1 ryanodine receptor; type 1-like ryanodine receptor; type 2 ryanodine receptor; unnamed protein product; VTSIP
Gensymboler RYR1, RYR2
Værtsarter Mouse
Immunogen Canine cardiac ryanodine receptor (RyR2).
Oprensningsmetode Protein G
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 100009536, 100009540, 100727848, 100731307, 114207, 20190, 20191, 396112, 403615, 421508, 606491, 6261, 6262, 689560
Målarter Amphibian, Canine, Chicken, Fish, Guinea Pig, Human, Mouse, Rabbit, Rat
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Produkttype Antibody
Form Liquid
Isotype IgG1
Vis mere Vis mindre
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.