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Tocris Bioscience™ Roscovitine
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Artikelnummer. 18767506
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Mængde:
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50mg
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Artikelnummer. Mængde
18767506 10 mg
18777136 50mg
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Artikelnummer. 18767506 Leverandør Tocris Bioscience™ Leverandørnr. 1332/10

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Beskrivelse

Potent, selective cyclin-dependent kinase inhibitor

Cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 μM for cdk5 to 0.8 μM for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin in vivo. Antimitotic.
TRUSTED_SUSTAINABILITY

Tekniske data

CAS 186692-46-6
Synonym roscovitine, seliciclib, r-roscovitine, rosco, 2-r-1-ethyl-2-hydroxyethylamino-6-benzylamino-9-isopropylpurine, unii-0es1c2kq94, insolution™ roscovitine, chembl14762, bmk1-e12
Mængde 10 mg
Molekylær formel C19H26N6O
Produkttitel
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