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Tocris Bioscience™ Roscovitine Product Code.: 18777136

Tocris Bioscience™ Roscovitine
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Product Code. 18777136
50mg, 50mg
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Quantity:
10 mg
50mg
Unit Size:
10mg
50mg
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Product Code. 18777136

Brand: Tocris Bioscience™ 1332/50

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This item is not returnable. View return policy

Potent, selective cyclin-dependent kinase inhibitor

Cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 ÎĽM for cdk5 to 0.8 ÎĽM for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin in vivo. Antimitotic.
Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol
CAS 186692-46-6
Synonym roscovitine, rosco, 2-r-1-ethyl-2-hydroxyethylamino-6-benzylamino-9-isopropylpurine, unii-0es1c2kq94, insolution roscovitine, chembl14762, bmk1-e12
Quantity 50mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Molecular Formula C19H26N6O
Formula Weight 354.45
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