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Tocris Bioscience™ Roscovitine

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Quantity:
10 mg
50mg
Unit Size:
10mg
50mg
Description
Cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 ÎĽM for cdk5 to 0.8 ÎĽM for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin in vivo. Antimitotic.
Greener Choice Claims
- Environmental benefits include:
- Ozone-Safe or Safe for the Ozone Layer

Specifications
Specifications
Chemical Name or Material | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
CAS | 186692-46-6 |
Synonym | roscovitine, rosco, 2-r-1-ethyl-2-hydroxyethylamino-6-benzylamino-9-isopropylpurine, unii-0es1c2kq94, insolution roscovitine, chembl14762, bmk1-e12 |
Quantity | 50mg |
Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
Molecular Formula | C19H26N6O |
Formula Weight | 354.45 |
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