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RNASET2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA532031
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: 293T, Jurkat, Raji. Predicted reactivity: Rhesus Monkey (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.Specifications
RNASET2 | |
Polyclonal | |
Unconjugated | |
RNASET2 | |
0610007O07Rik; 4833423A10Rik; 4930532K22Rik; bA514O12.3; C79750; Ribonuclease 6; Ribonuclease 6-A; Ribonuclease 6-B; Ribonuclease T2; ribonuclease T2A; Ribonuclease T2-A; Ribonuclease T2-B; RNase T2; RNASE6PL; RNASET2; Rnaset2a; Rnaset2b; rnt2; RP11-514O12.3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8635 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.81 mg/mL | |
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
O00584 | |
RNASET2 | |
Recombinant fragment corresponding to a region within amino acids 26 and 256 of Human Ribonuclease T2 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |