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Rhosin hydrochloride, MedChemExpress

Artikelnummer. 16495268
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Mængde:
5 mg
10 mg
Pakningsstørrelse:
5mg
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16495268 10 mg -
16457987 5 mg 5mg
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Artikelnummer. 16495268 Leverandør Medchem Express Leverandørnr. HY12646

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Beskrivelse

MedChemExpress Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ∼ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.

Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ∼ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.

Tekniske data

Kemisk navn eller materiale Rhosin hydrochloride
Fysisk form Solid
CAS 1281870-42-5
Farve Yellow
Mængde 10 mg
Renhedsgrad noter Research
Molekylær formel C20H19ClN6O
Til brug med (applikation) Cancer-Kinase/protease
Opløselighedsinformation DMSO : 100 mg/mL (253.25 mM; Need ultrasonic) ∣H2O : 16.67 mg/mL (42.22 mM; Need ultrasonic)
SMIL O=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4.[H]Cl
Molekylvægt (g/mol) 394.86
Formel vægt 394.86
Procent renhed 99.67%
Grad Research
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Research purposes only

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