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Retinoic acid, MedChemExpress

Artikelnummer. 16421746
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Artikelnummer. 16421746 Leverandør Medchem Express Leverandørnr. HY14649

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MedChemExpress Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

Tekniske data

Kemisk navn eller materiale Retinoic acid
CAS 302-79-4
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C20H28O2
Mængde 500 mg
Synonym Vitamin A acid all-trans-Retinoic acid ATRA
Opløselighedsinformation DMSO : 50 mg/mL (166.42 mM; ultrasonic and warming and heat to 60°C)
SMIL CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
Molekylvægt (g/mol) 300.44
Formel vægt 300.44
Procent renhed 96.11%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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