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Tocris Bioscience™ RepSox
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Artikelnummer. 18034202
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Mængde:
10 mg
50 mg
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Artikelnummer. Mængde
18034202 10 mg
18014492 50 mg
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Artikelnummer. 18034202 Leverandør Tocris Bioscience™ Leverandørnr. 3742/10

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Beskrivelse

Potent and selective inhibitor of TGF-βRI

RepSox is a potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 values are 4 and 23 nM for TGF-β type I receptor autophosphorylation and binding respectively). Selective for TGF-β type I receptor over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). Enhances the efficiency of cellular reprogramming; replaces Sox2 by inducing Nanog expression.

RepSox synthesized to Ancillary Material Grade also available.

For more information about how RepSox may be used, see our protocols: Highly Efficient Generation of CiPSCs from MEFs, Generation of β cells from hPSCs, Reprogramming MEFs into Skeletal Muscle Progenitors .

TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 446859-33-2
Molekylær formel C17H13N5

Tekniske data

Kemisk navn eller materiale RepSox
Mængde 10 mg
Formel vægt 287.32
Renhed >99%
Molekylvægt (g/mol) 287.326
Produkttitel
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