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Tocris Bioscience™ RECTAS Artikelnummer.: 18708626

Tocris Bioscience™ RECTAS
GREENER_CHOICE

Artikelnummer. 18708626
10 mg
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Mængde:
10 mg
50 mg
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Artikelnummer. 18708626

Brand: Tocris Bioscience™ 7679/10

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IKBKAP pre-mRNA splicing modulator

RECTAS (rectifier of aberrant splicing) is a pre-mRNA splicing modulator of the IKBKAP (inhibitor of κ light polypeptide gene enhancer in B-cells, kinase complex associated protein) gene. It corrects aberrant IKBKAP splicing in vitro in cellular models of familial dysautonomia and in vivo in transgenic mice. In combination with Phenylbutyric acid (Cat. No. 2682), RECTAS rescues PARK7 aberrant splicing and neuronal cell loss in a midbrain organoid model of familial Parkinson's disease. Orally bioavailable and brain penetrant.
Greener Choice-anprisninger
  • undefined
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale 2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
CAS 101862-47-9
Mængde 10 mg
Mål DNA, RNA and Protein Synthesis Compounds
Molekylær formel C10H8ClN5O
Renhed 0.98
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