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Tocris Bioscience™ Rapamycin
Beskrivelse
Rapamycin is a antifungal and immunosuppressant. Specific inhibitor of mTOR (mammalian target of Rapamycin). Complexes with FKBP-12 and binds mTOR inhibiting its activity. Inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase. Induces autophagy in yeast and mammalian cell lines. Drives hPSC differentiation to mesendoderm and blood progenitor cells. Also used as a chemical dimerizer; rapamycin and GA3-AM (Cat. No. 5407) chemically inducible dimerization systems are orthogonal. Inhibits MERS-CoV infection of Huh7 cells in a plaque reduction assay. Enhances lentiviral transduction of hematopoietic stem cells.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | Rapamycin |
| CAS | 53123-88-9 |
| Mængde | 1 mg |
| Molekylær formel | C51H79NO13 |
| Formel vægt | 914.18 |
| Produkttype | Rapamycin |
| Renhed | 98% |
| Molekylvægt (g/mol) | 914.187 |
Produkttitel
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