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Invitrogen™ RAD51 Polyclonal Antibody
Beskrivelse
Recommended positive controls: yeast. Predicted reactivity: Yeast (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
Tekniske data
Tekniske data
| Antigen | RAD51 |
| Applikationer | Western Blot |
| Klassifikation | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugeret | Unconjugated |
| Formulering | PBS with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | Rad51 |
| Genadgangsnr. | P25454 |
| Gene Alias | AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754 |
| Gensymboler | Rad51 |
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Produkttitel
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