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NTRK1 (phospho Y757), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Beskrivelse
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
Tekniske data
Tekniske data
| Antigen | NTRK1 |
| Applikationer | Immunohistochemistry (PFA fixed) |
| Klassifikation | Polyclonal |
| Konjugeret | Unconjugated |
| Oversigt | Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1. |
| Fortynding | Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide) |
| Gene | NTRK1 |
| Gene Alias | DKFZp781I14186/MTC/TRK/TRK1/TRKA/p140-TrkA |
| Gensymboler | NTRK1 |
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For Research Use Only
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