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STEMCELL Technologies Quercetin (Hydrate)

Artikelnummer. 17170292
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Mængde:
5 g
10 g
Pakningsstørrelse:
10g
5g
Artikelnummer. Mængde unitSize
17170292 5 g 5g
17180292 10 g 10g
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Regulatorisk: Dette produkt falder ind under Lov om kemiske stoffer og produkter - lovbekendtgørelse nr. 1755 af 22. december 2006. Hvis det er relevant, skal kunden fremskaffe en licens før levering.

Artikelnummer. 17170292

Brand: STEMCELL Technologies 73932

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mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases

  • Quercetin inhibits phosphoinositide 3-kinase isoforms (beta: IC50 = 5.4 μM; gamma: IC50 = 2.4 μM; delta: IC50 = 3.0 μM) and SRC kinases but only shows slight inhibitory activity against serine/threonine kinases ERK1/2 and p38 alpha, as well as protein kinase C (Navarro-Nunez et al.)
  • Stimulates glycolytic metabolism and promotes reprogramming of somatic cells (Zhang et al.)
  • Enhances reprogramming of human primary somatic cells to induced pluripotent stem cells (Zhu et al.)
  • Induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation (Triantafyllou et al.)
  • Promotes apoptosis of glioblastoma cells when used together with temozolomide (Sang et al.)
  • Reduces tumorigenicity of pancreatic cancer cells (Fan et al.)

Specifications

CAS 849061-97-8
Mængde 5 g
Molekylær formel C15H10O7 · XH2O
Renhed ≥95%
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