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Tocris Bioscience™ Pyridostatin pentahydrochloride
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Artikelnummer. 18744719
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Mængde:
10 mg
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Artikelnummer. Mængde
18744719 10 mg
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Artikelnummer. 18744719 Leverandør Tocris Bioscience™ Leverandørnr. 4763/10

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Beskrivelse

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).
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Tekniske data

CAS 1781882-65-2
Mængde 10 mg
Molekylær formel 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride
Produkttype Pyridostatin pentahydrochloride
Renhed 95%
Molekylvægt (g/mol) M.W. (Observed): 778.94
Inhibitorer Pyridostatin pentahydrochloride

For Research Use Only

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